GLP-1 Muscle Loss: 3 Simple Tests to Check Your Strength w/ Mark Hamrick
36:15 · GLP-1 Hub: Support, Community, and Weight Loss · 2026-09-21
Send us Fan Mail What can getting out of a chair tell you about your muscle health? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins muscle and bone researcher Mark Hamrick to explore staying strong during GLP-1 weight loss, perimenopause, and menopause. You'll learn what three simple assessments can reveal about physical function, and why muscle size alone doesn't tell the whole story. Mark explains the differences between muscle mass, quality, strength, and power, and how they connect to everyday movement and healthy aging. Ana shares her own assessment results and asks whether her regular exercise routine is enough. They also discuss bone density, fall risk, and finding an approach to exercise that works when pain or physical limitations get in the way. **IN THIS EPISODE** - Why losing muscle size doesn't necessarily mean losing the same amount of strength - What chair rises, single-leg balance, and walking speed can tell you about physical function - How menopause, sleep, and activity levels enter the muscle-health conversation - Resistance training, protein, and the research Mark discusses on creatine - Adapting exercise with help from a physical therapist when movement is painful - Bone density, DEXA scans, fall risk, and questions to bring to your healthcare provider **ABOUT THE GUEST** Mark Hamrick is president and co-founder of Velogenix and a former Regents Professor at the Medical College of Georgia. His research on muscle and bone aging has received NIH funding over the last two decades. He has published more than 225 peer-reviewed papers and advised NASA on muscle and bone loss in space. At Velogenix, he is applying that experience to tools for quickly assessing muscle health at home. **CONNECT WITH MARK** Website: https://velogenix.com LinkedIn: https://www.linkedin.com/in/mark-hamrick-44b287121/ **SPONSORS** Velogenix, co-founded by our guest, Mark Hamrick. Project Aeterna offers at-home assessments of strength, balance, and walking speed. Try the free baseline test, or use code OFF for $50 off your first year of Pro. https://velogenix.com Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month. https://tydewellness.com/GLP1Hub **CHAPTERS** 00:00 Why muscle and bone health deserve attention 01:27 Meet Mark Hamrick 02:39 Three simple assessments of physical function 05:11 Muscle size, quality, and the menopause transition 09:59 The connection between muscle and longevity 12:21 Walking, strength training, and protein 13:57 Everyday signs your strength may be changing 15:08 Sponsor: Tyde Wellness 16:33 What to do with your assessment results 17:48 Exercising with pain or physical limitations 19:13 Ana's results: Is regular exercise enough? 22:22 Sitting, standing, and moving more 24:08 Bone density, DEXA scans, and fall risk 28:46 Beyond the Shot guide 29:47 Mark's three takeaways for muscle and bone health 34:19 Try Project Aeterna and connect with Mark MORE FROM GLP-1 HUB 📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com 🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show. 🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com 📷 Follow on Instagram: @glp1hub 📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show. *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.